Human SCAMP5 activation kit by CRISPRa

Cat# GA116257

Size : 1kit

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Human SCAMP5 activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SCAMP5
Locus ID 192683
Components

GA116257G1, SCAMP5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116257G2, SCAMP5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116257G3, SCAMP5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001178111, NM_001178112, NM_138967, NR_033660
UniProt ID Q8TAC9
Synonyms DKFZp686L1799; MGC24969
Summary Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway.[UniProtKB/Swiss-Prot Function]
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SKU Description Size
KN405149 SCAMP5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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