NADPH oxidase inhibitor; autophagy inhibitor; anti-inflammatory.||Hydroxychloroquine sulfate has been used:|• as an inhibitor of autophagy to treat cells for apoptosis assay to study the role of pirarubicin induced autophagy in bladder cancer cell line|• to evaluate the antiviral mechanism of hydroxychloroquine against DENV-2 (dengue virus-2) infection by immunofluorescence assay|• to inhibit lysosome fusion with the autophagosome|• for treating rheumatoid arthritis and systemic lupus erythematosus.|• as an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used as a malaria treatment.||Synonyms:|2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol; 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate, Hydroxycloroquine sulfate; Ercoquin; Plaquenil Sulfate; Quensyl||CAS Number:|747-36-4|Free base: 118-42-3||Molecular Weight:|433.95||Molecular Formula:|C₁₈H₂₈ClN₃O₅S||Purity:|≥98%||Appearance:|White to off-white solid||Melting Point:|250-251ºC||Storage and Stability:|Store at 4ºC. Stable for 12 months after receipt.