INDY
Cat# orb1473181-100mg
Size : 100mg
Brand : Biorbyt
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INDY
Catalog Number: orb1473181
| Catalog Number | orb1473181 |
|---|---|
| Category | Small Molecules |
| Description | INDY is a potent and ATP-competitive Dyrk1A and Dyrk1B inhibitor with IC50s of 0.24 μM and 0.23 μM, respectively. INDY binds in the ATP pocket of the enzyme and has a Ki value of 0.18 μM for Dyrk1A. INDY sharply reduces the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells. |
| CAS Number | [1169755-45-6] |
| MW | 235.3 |
| SMILES | CC(/C=C1SC2=CC=C(O)C=C2N\1CC)=O |
| Formula | C12H13NO2S |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |