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> inhA Recombinant Protein

inhA Recombinant Protein

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Cat# OPCA02159-1MG

Size : 1mg

Brand : Aviva Systems Biology

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Phone : +1 850 650 7790
Datasheets/ManualsPrintable datasheet for INHA Recombinant Protein (Mycobacterium tuberculosis) (OPCA02159) (OPCA02159)
Product Info
Predicted Species ReactivityMycobacterium tuberculosis
Product FormatLiquid or Lyophilized powder
HostMycobacterium tuberculosis
Reconstitution and Storage-20°C or -80°C
Formulation20 mM Tris-HCl based buffer, pH 8.0
PurityGreater than 90% as determined by SDS-PAGE.
Peptide SequenceMTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL
Protein SequenceMTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL
Storage BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
SourceE.coli
Protein Range1-269 aa
TagN-terminal 6xHis-SUMO-tagged
ReferencePyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis.He X., Alian A., Stroud R., Ortiz de Montellano P.R.J. Med. Chem. 49:6308-6323(2006)
Gene SymbolINHA
Alias SymbolsFAS-II enoyl-ACP reductase;NADH-dependent 2-trans-enoyl-ACP reductase.
Protein NameEnoyl-[acyl-carrier-protein] reductase [NADH]
Description of TargetEnoyl-ACP reductase of the type II fatty acid syntase (FAS-II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans-enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates. The mycobacterial FAS-II system utilizes the products of the FAS-I system as primers to extend fatty acyl chain lengths up to C56, forming the meromycolate chain that serves as the precursor for final mycolic acids.
Uniprot IDP9WGR0
Protein Size (# AA)Recombinant
Molecular Weight44.5 kDa