IRS-3 Polyclonal Antibody, HRP Conjugated
Cat# bs-0186R-HRP
Size : 100ul
Brand : Bioss
IRS-3 Polyclonal Antibody, HRP Conjugated
Applications
Reactivity
Overview | |
Catalog # | bs-0186R-HRP |
Product Name | IRS-3 Polyclonal Antibody, HRP Conjugated |
Applications | WB, ELISA, IHC-P, IHC-F |
Reactivity | Human, Mouse, Rat, Pig |
Specifications | |
Conjugation | HRP |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from rat IRS-3 |
Immunogen Range | 261-360/494 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 84021 |
Subcellular location | Cytoplasm, Cell membrane |
Synonyms | IRS1--Insulin receptor substrate-3; IRS3; IRS-3; IRS3. |
Background | The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |
IHC-P | 1:200-400 |
IHC-F | 1:100-500 |