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> Leucomalachite green-d5 [947601-82-3]

Leucomalachite green-d5 [947601-82-3]

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Cat# HY-D0300S

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Brand : MedChemExpress

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Leucomalachite green-d5 is the deuterium labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].

For research use only. We do not sell to patients.

Leucomalachite green-d<sub>5</sub> Chemical Structure

Leucomalachite green-d5 Chemical Structure

CAS No. : 947601-82-3

This product is a controlled substance and not for sale in your territory.

Description

Leucomalachite green-d5 is the deuterium labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Leucomalachite green-d5 Related Antibodies
Molecular Weight

335.50

Formula

C23H21D5N2
CAS No.

947601-82-3
Unlabeled CAS

129-73-7
SMILES

CN(C)C(C=C1)=CC=C1C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C3=CC=C(C=C3)N(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief]

    [2]. Ya-hui Li, et al. Development of a group selective molecularly imprinted polymers based solid phase extraction of malachite green from fish water and fish feed samples. Anal Chim Acta. 2008 Aug 29;624(2):317-25.;Kohji Ishihama, et al. Floating aerial blood mists in the operating room. J Hazard Mater. 2010 Sep 15;181(1-3):1179-81.  [Content Brief]

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Ya-hui Li, et al. Development of a group selective molecularly imprinted polymers based solid phase extraction of malachite green from fish water and fish feed samples. Anal Chim Acta. 2008 Aug 29;624(2):317-25.;Kohji Ishihama, et al. Floating aerial blood mists in the operating room. J Hazard Mater. 2010 Sep 15;181(1-3):1179-81.

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Leucomalachite green-d5 Related Classifications

  • Others
  • Fluorescent Dye Isotope-Labeled Compounds

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Leucomalachite green-d5947601-82-3Fluorescent DyeIsotope-Labeled CompoundsInhibitorinhibitorinhibit