Mouse DPP9 (Dipeptidyl Peptidase 9) Sandwich ELISA Kit

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Dpp9
Gene ID:	224897
Uniprot ID:	DPP9_MOUSE
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Detected in kidney, skin, brain, thymus and liver (at protein level).
Post Translational Modifications
Function	Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. Acts as a key inhibitor of caspase-1-dependent monocyte and macrophage pyroptosis in resting cells by preventing activation of NLRP1 and CARD8. Sequesters the cleaved C-terminal part of NLRP1 and CARD8, which respectively constitute the active part of the NLRP1 and CARD8 inflammasomes, in a ternary complex, thereby preventing their oligomerization and activation. The dipeptidyl peptidase activity is required to suppress NLRP1 and CARD8.however, neither NLRP1 nor CARD8 are bona fide substrates of DPP9, suggesting the existence of substrate(s) required for NLRP1 and CARD8 inhibition.
Protein Name	Dipeptidyl Peptidase 9 Dp9 Dipeptidyl Peptidase Ix Dpp Ix Dipeptidyl Peptidase-Like Protein 9 Dplp9
Database Links
Cellular Localisation	Cytoplasm Cytosol
Alternative ELISA Names	Dipeptidyl Peptidase 9 ELISA kit Dp9 ELISA kit Dipeptidyl Peptidase Ix ELISA kit Dpp Ix ELISA kit Dipeptidyl Peptidase-Like Protein 9 ELISA kit Dplp9 ELISA kit Dpp9 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance