Mouse Fadd activation kit by CRISPRa
Cat# GA201350
Size : 1kit
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Mouse Fadd activation kit by CRISPRa
SKU
GA201350
Fadd CRISPRa kit - CRISPR gene activation of mouse Fas (TNFRSF6)-associated via death domain
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Fadd |
| Locus ID | 14082 |
| Components | GA201350G1, Fadd gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201350G2, Fadd gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201350G3, Fadd gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_010175 |
| UniProt ID | Q61160 |
| Synonyms | Mort1/FADD |
| Summary | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).[UniProtKB/Swiss-Prot Function] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN505495 | Fadd - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.