General Info
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.067ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This HSPb6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
Information
| Gene Symbol: | Hspb6 |
| Gene ID: | 243912 |
| Uniprot ID: | HSPB6_MOUSE |
| Sample Type: | tissue homogenates or other biological fluids. |
Description
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylated at Ser-16 by PKA and probably PKD1K.required to protect cardiomyocytes from apoptosis. |
| Function | Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity. |
| Protein Name | Heat Shock Protein Beta-6Hspb6 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusSecretedTranslocates To Nuclear Foci During Heat Shock |
| Alternative ELISA Names | Heat Shock Protein Beta-6 ELISA kitHspb6 ELISA kitHspb6 ELISA kitGm479 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance