OCT4 (1-265, His-tag) Human Protein
Cat# AR50772PU-N
Size : 500ug
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OCT4 (1-265, His-tag) Human Protein
SKU
AR50772PU-N
OCT4 (1-265, His-tag) human recombinant protein, 0.5 mg
3 Weeks*
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | Protein Sequence MGSSHHHHHH SSGLVPRGSH MHFYRLFLGA TRRFLNPEWK GEIDNWCVYV LTSLLPFKIQ SQDIKALQKE LEQFAKLLKQ KRITLGYTQA DVGLTLGVLF GKVFSQTTIC RFEALQLSFK NMCKLRPLLQ KWVEEADNNE NLQEICKAET LVQARKRKRT SIENRVRGNL ENLFLQCPKP TLQQISHIAQ QLGLEKDVVR VWFCNRRQKG KRSSSDYAQR EDFEAAGSPF SGGPVSFPLA PGPHFGTPGY GSPHFTALYS SVPFPEGEAF PPVSVTTLGS PMHSN |
| Tag | His-tag |
| Predicted MW | 32.2 kDa |
| Concentration | lot specific |
| Purity | >85% by SDS - PAGE |
| presentation_state | Purified |
| Buffer | Presentation State: This purified protein is available in a denatured form, making it less suitable for functional studies. Denatured proteins are better suited for applications like Western Blot (WB) or imaging assays. State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
| Preparation | Liquid purified protein |
| Protein Description | Recombinant human OCT4 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Reference Data | |
| RefSeq | NP_001167002 |
| Locus ID | 5460 |
| UniProt ID | M1S623 |
| Cytogenetics | 6p21.33 |
| Synonyms | POU domain, class 5, transcription factor 1 isoform 2, POU5F1, MGC22487, OCT3, OCT4, OTF3, OTF4 |
| Summary | This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013] |
| Protein Families | Adult stem cells, Cancer stem cells, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.