Recombinant Human TNF alpha
Cat# RP0440H-025
Size : 25ug
Brand : Kingfisher Biotech
Contact local distributor :
Phone : +1 850 650 7790
Tumor necrosis factor alpha (TNFSF2) is a member of the TNF Superfamily. It is produced chiefly by activated macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells, cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. The primary role of TNF alpha is in the regulation of immune cells. TNF alpha, being an endogenous pyrogen, is able to induce fever, to induce apoptotic cell death, to induce sepsis (through IL-1 & IL-6 production), to induce cachexia, induce inflammation, and to inhibit tumorigenesis and viral replication.
Alternate Names -
Catalog No.:
RP0440H-025
Quantity:
25 ug
Source:
Human TNF alpha was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
MW:
Human TNF alpha has a predicted molecular weight of 17.2 kDa.
Protein Sequence:
VRSSSRTPSD KPVAHVVANP QAEGQLQWLN RRANALLANG VELRDNQLVV PSEGLYLIYS QVLFKGQGCP STHVLLTHTI SRIAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYL GGVFQLEKGD RLSAENRPDY LDFAESGQVY FGIIAL (156)
Alias:
TNFSF2
Country of Origin:
USA
Applications:
The Human TNF endotoxin-free recombinant protein can be used in cell culture, as an ELISA Standard, and as a Western Blot Control.