Sofosbuvir [1190307-88-0]
Cat# HY-15005-5mg
Size : 5mg
Brand : MedChemExpress
Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM.
For research use only. We do not sell to patients.
Sofosbuvir Chemical Structure
CAS No. : 1190307-88-0
This product is a controlled substance and not for sale in your territory.
Based on 105 publication(s) in Google Scholar
Other Forms of Sofosbuvir:
- PSI-7976 In-stock
- Sofosbuvir impurity C In-stock
- Sofosbuvir impurity A In-stock
- Sofosbuvir-d6 In-stock
- Enantiomer of Sofosbuvir In-stock
- Sofosbuvir-13C,d3 Get quote
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Sofosbuvir purchased from MedChemExpress. Usage Cited in: Eur J Med Chem. 2018 Jan 1;143:1053-1065. [Abstract]
- Huh7.5 cells are infected with HCV and simultaneously treated with 7f (10 μM) or DAA (0.04 μM Simeprevir, 0.08 μM Sofosbuvir, or 16 pM Daclatasvir) or 7f plus DAA.
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Sofosbuvir purchased from MedChemExpress. Usage Cited in: Eur J Med Chem. 2018 Jan 1;143:1053-1065. [Abstract]
- GS4.3 cells are treated with 7f (20 μM), or Telaprevir (0.5μM), Sofosbuvir (0.8 μM), Daclatasvir (0.15 μM) or solvent control for 6 days.
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Sofosbuvir purchased from MedChemExpress. Usage Cited in: Biomed Res Int. 2017;2017:1236801. [Abstract]
- Huh7.5 (HCV+) cells are treated with 1 μM of Sofosbuvir or solvent control. At 24 hours, the cells are washed and continuously incubated with fresh culture media containing drugs again for 48 hours. The cultural supernatants are then harvested and directly incubated to naïve Huh7.5 cells. After been passaged 1~3 times, the newly infected cells are treated with 1 μM of Sofosbuvir for 72 hours. Intracellular proteins are extracted and detected with WB.
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Sofosbuvir purchased from MedChemExpress. Usage Cited in: J Med Chem. 2016 Nov 23;59(22):10268-10284. [Abstract]
- Huh7.5 cells are infected with HCV (45 IU/cell) and simultaneously treated with Simeprevir (A, 0.025 μM), Sofosbuvir (B, 0.1 μM), or Daclatasvir (C, 16 pM) alone or with 1 (6.25 μM).