TDP43 (TARDBP) Human shRNA Plasmid Kit (Locus ID 23435)

Cat# TR308946

Size : 1kit

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TDP43 (TARDBP) Human shRNA Plasmid Kit (Locus ID 23435)

Specifications
Product Data
Locus ID 23435
Synonyms ALS10; TDP-43
Vector pRS
E. coli Selection Ampicillin
Format Retroviral plasmids
Components TARDBP - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 23435). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_007375, NM_007375.1, NM_007375.2, NM_007375.3, BC095435, BC095435.1, BC001487, BC059955, BC071657, BM716882, NM_007375.4
UniProt ID Q13148
Summary HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@clinisciences.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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