Uridine triphosphate (trisodium salt) [19817-92-6]
Cat# HY-W013093-1ml
Size : 10mM/1mL
Brand : MedChemExpress
Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors.
For research use only. We do not sell to patients.
Uridine triphosphate trisodium salt Chemical Structure
CAS No. : 19817-92-6
This product is a controlled substance and not for sale in your territory.
Based on 2 publication(s) in Google Scholar
Other Forms of Uridine triphosphate trisodium salt:
- Uridine triphosphate Get quote
Description |
Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors[1][2]. |
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IC50 & Target |
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In Vitro |
Uridine triphosphate (UTP) (0, 10, 100, 250, 500, and 1000 µM; 2, 4, 6, 8, 10, and 12 h) trisodium salt enhances RT4-D6P2T cells migration and wound repair. Uridine triphosphate trisodium salt induces Schwannoma cell migration through activation of P2Y2 receptors and through the increase of extracellular MMP-2 activation and expression[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot Analysis[2]
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In Vivo |
Uridine triphosphate (UTP) (0.44-4.4 µg/kg; i.v.; once) trisodium salt reduces infarct size and improves rat heart function after myocardial infarct[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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Molecular Weight |
550.09 |
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Formula |
C9H12N2Na3O15P3 |
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CAS No. |
19817-92-6 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(OP(OP([O-])([O-])=O)([O-])=O)(O)=O.[3Na+] |
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Structure Classification |
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Initial Source |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Solvent & Solubility |
In Vitro:
H2O : 75 mg/mL (136.34 mM; Need ultrasonic) DMSO : 10 mg/mL (18.18 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
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Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
For the following dissolution methods, please prepare the working solution directly.
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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Purity & Documentation |
Purity: ≥97.0% |
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References |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO / H2O | 1 mM | 1.8179 mL | 9.0894 mL | 18.1788 mL | 45.4471 mL |
5 mM | 0.3636 mL | 1.8179 mL | 3.6358 mL | 9.0894 mL | |
10 mM | 0.1818 mL | 0.9089 mL | 1.8179 mL | 4.5447 mL | |
15 mM | 0.1212 mL | 0.6060 mL | 1.2119 mL | 3.0298 mL | |
H2O | 20 mM | 0.0909 mL | 0.4545 mL | 0.9089 mL | 2.2724 mL |
25 mM | 0.0727 mL | 0.3636 mL | 0.7272 mL | 1.8179 mL | |
30 mM | 0.0606 mL | 0.3030 mL | 0.6060 mL | 1.5149 mL | |
40 mM | 0.0454 mL | 0.2272 mL | 0.4545 mL | 1.1362 mL | |
50 mM | 0.0364 mL | 0.1818 mL | 0.3636 mL | 0.9089 mL | |
60 mM | 0.0303 mL | 0.1515 mL | 0.3030 mL | 0.7575 mL | |
80 mM | 0.0227 mL | 0.1136 mL | 0.2272 mL | 0.5681 mL | |
100 mM | 0.0182 mL | 0.0909 mL | 0.1818 mL | 0.4545 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Uridine triphosphate trisodium salt Related Classifications
- Oligonucleotides
- Nucleotides and their Analogs
- Metabolic Enzyme/Protease GPCR/G Protein
- Endogenous Metabolite P2Y Receptor