UVRAG (389-699) Mouse Monoclonal Antibody [Clone ID: 1H4]
Specifications
Product Data | |
Clone Name | 1H4 |
Applications | IP, WB |
Recommended Dilution | Western blot: 1 μg/ml for chemiluminescence detection system. Positive Control: HeLa, Jurkat (Human), NIH/3T3, WR19L (Mouse), Rat1 (Rat), and CHO (Hamster). Immunoprecipitation: 5 μg/300 μl of cell extract from 1 x 107 cells. |
Reactivities | Hamster, Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Recombinant protein corresponding to amino acid residues 389 to 699 of Human UVRAG |
Specificity | This antibody reacts with UVRAG. |
Formulation | PBS containing 50% glycerol, pH 7.2. No preservative is contained. State: Azide Free State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A Agarose |
Conjugation | Unconjugated |
Storage | Upon receipt, store (in aliqouts) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Gene Name | UV radiation resistance associated |
Database Link | |
Background | Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. UVRAG (UV irradiation resistance-associated gene) has been identified as an essential component of the Beclin 1-PI3KC3 complex that suppresses tumorigenicity of human colon and promotes Beclin 1 dependent autophagy. |
Synonyms | p63 |
Note | This product was originally produced by MBL International. |
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