5-Azacytidine [320-67-2]
Referencia HY-10586-100mg
embalaje : 100mg
Marca : MedChemExpress
5-azacytidine (azacitidine; 5-azaC; ladakamycine) est un analogue nucléosidique de la cytidine qui inhibe spécifiquement la méthylation de l'ADN. 5-azacytidine est incorporée dans l'ADN pour piéger de manière covalente les ADN méthyltransférases et contribue à inverser les changements épigénétiques. 5-azacytidine induit l'autophagie cellulaire.
5-Azacytidin (Azacitidin; 5-AzaC; Ladakamycin) ist ein Nukleosidanalogon von Cytidin, das spezifisch die DNA-Methylierung hemmt. 5-Azacytidin wird in die DNA eingebaut, um DNA methyltransferases kovalent einzufangen, und trägt zur Umkehrung epigenetischer Veränderungen bei. 5-Azacytidin induziert die Zellautophagie.
5-Azacytidine (Azacitidine; 5-AzaC; Ladakamycin) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation. 5-Azacytidine is incorporated into DNA to covalently trap DNA methyltransferases and contributes to reverse epigenetic changes. 5-Azacytidine induces cell autophagy.
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5-Azacytidine Estructura química
No. CAS : 320-67-2
This product is a controlled substance and not for sale in your territory.
Based on 88 publication(s) in Google Scholar
Other Forms of 5-Azacytidine:
- 5-Azacytidine-15N4 Obtener un presupuesto
- 5-Azacytidine (Standard) Obtener un presupuesto
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5-Azacytidine purchased from MedChemExpress. Usage Cited in: Int J Biol Macromol. 2022.
- 5-azacytidine (5-AzaC; 5 μM; 1, 2, 3 days) results in an increase in the expression of MYOD1 and MYOG during myoblast differentiation.
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5-Azacytidine purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2018 Jan 26;9(2):129. [Abstract]
- The effects of treatment with the indicated epigenetic inhibitors on cleaved PARP (Clv-PARP) expression in both PC9/ER and HCC827/ER cells. β-actin is used as a loading control.