A549 cells
Referencia C0016002
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Disease:
Lung carcinoma The cells can synthesise lecithin utilising the cytidine diphosphocholine pathway Homo sapiens Lung Epithelial Adherent This is a hypotriploid human cell line Male, Caucasian, 58 yrs of age F-12K Nutrient Mixture (Kaighn's Modification) + 10% FBS 1:3 to 1:8 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C Complete culture medium supplemented with 5% (v/v) DMSO Bacteria: Negative Yeast: Negative Mycoplasma: Negative HIV: Negative Hepatitis B: Negative Hepatitis C: Negative If use of this culture results in a scientific publication, it should be cited in the publication as: A549 (AddexBio C0016002) A427 cells A549 cells Calu3 cells H1650 cells H1703 cells H1975 cells H226 cells H23 cells H460 cells H520 cells HCC4006 cells SW1573 cells 3D4/2 cells BEAS-2B cells MRC-5 cells Mv 1 Lu cells RLE-6TN cells Origin:
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G6PD, B DNA Profile (STR):
Amelogenin: X,Y CSF1PO: 10,12 D13S317: 11 D16S539: 11,12 D5S818: 11 D7S820: 8,11 THO1: 8,9.3 TPOX: 8,11 vWA: 14 Related cells by Organ:
References for A549 cells:
1. Armstrong, D. A., Phelps, L. N., and Vincenti, M. P. CCAAT enhancer binding protein-beta regulates matrix metalloproteinase-1 expression in interleukin-1beta-stimulated A549 lung carcinoma cells. Mol Cancer Res, 7: 1517-1524, 2009.
2. Tomankova, K., Kolarova, H., Bajgar, R., Jirova, D., Kejlova, K., and Mosinger, J. Study of the photodynamic effect on the A549 cell line by atomic force microscopy and the influence of green tea extract on the production of reactive oxygen species. Ann N Y Acad Sci, 1171: 549-558, 2009.
3. Chuang, C. Y., Chen, T. L., and Chen, R. M. Molecular mechanisms of lipopolysaccharide-caused induction of surfactant protein-A gene expression in human alveolar epithelial A549 cells. Toxicol Lett, 191: 132-139, 2009.
4. Wei, C. W., Lin, C. C., Yu, Y. L., Lin, C. Y., Lin, P. C., Wu, M. T., Chen, C. J., Chang, W., Lin, S. Z., Chen, Y. L., and Harn, H. J. n-Butylidenephthalide induced apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2alpha and telomerase activity. Acta Pharmacol Sin, 30: 1297-1306, 2009.
5. Su, J. C., Lin, K. L., Chien, C. M., Lu, C. M., Chen, Y. L., Chang, L. S., and Lin, S. R. Novel indoloquinoline derivative, IQDMA, induces G(2)/M phase arrest and apoptosis in A549 cells through JNK/p38 MAPK signaling activation. Life Sci, 85: 505-516, 2009.
6. Ding, X. L., Zhang, H. Y., Qi, L., Zhao, B. X., Lian, S., Lv, H. S., and Miao, J. Y. Synthesis of novel pyrazole carboxamide derivatives and discovery of modulators for apoptosis or autophagy in A549 lung cancer cells. Bioorg Med Chem Lett, 19: 5325-5328, 2009.