Angiotensin Converting Enzyme 2 (ACE2) (N-term) Rabbit Polyclonal Antibody
Referencia AP22858PU-N
embalaje : 50ug
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| Product Data | |
| Application | ELISA, IHC, WB |
|---|---|
| Application | ELISA. Immunohistochemistry on Paraffin Sections: 2.5 µg/ml. Western Blot: 0.5 - 2 µg/ml. |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | ACE2 antibody was raised against synthetic peptide |
| Specificity | This antibody reacts to Angiotensin I Converting Enzyme 2 (ACE2). |
| Buffer | PBS containing 0.02% sodium azide State: Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Immunoaffinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Gene Name | angiotensin I converting enzyme 2 |
| Database Link | |
| Background | Angiotensin-Converting Enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function. |
| Synonyms | Angiotensin-converting enzyme 2 |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.