General Info
| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Rat/Mouse/Chicken |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Cytochrome P450 2A6 (1-50 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | CYP2A6 |
| Gene ID: | 1548 |
| Uniprot ID: | CP2A6_HUMAN |
| Immunogen Region: | 1-50 aa |
| Specificity: | CYP2A6 Polyclonal Antibody detects endogenous levels of CYP2A6 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human Cytochrome P450 2A6 at the amino acid range 1-50 |
Description
| Function | Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity. |
| Protein Name | Cytochrome P450 2a61 -4-Cineole 2-Exo-MonooxygenaseCypiia6Coumarin 7-HydroxylaseCytochrome P450 Iia3Cytochrome P450(I |
| Database Links | Reactome: R-HSA-211981Reactome: R-HSA-211999 |
| Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinMicrosome Membrane |
| Alternative Antibody Names | Anti-Cytochrome P450 2a6 antibodyAnti-1 -4-Cineole 2-Exo-Monooxygenase antibodyAnti-Cypiia6 antibodyAnti-Coumarin 7-Hydroxylase antibodyAnti-Cytochrome P450 Iia3 antibodyAnti-Cytochrome P450(I antibodyAnti-CYP2A6 antibodyAnti-CYP2A3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance