AQP4 Antibody

Referencia OAAB21710

embalaje : 100ul

Marca : Aviva Systems Biology

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Datasheets/ManualsPrintable datasheet for anti-AQP4 (OAAB21710) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Pig
Product FormatLiquid. 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
ClonalityPolyclonal
HostRabbit
ApplicationWB, FC, IHC-P
::Cellular Location: Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endosome membrane. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection. Note=Activation of the vasopressin receptor AVPR1A triggers AQP4 phosphorylation at Ser-180 and promotes its internalization from the cell membrane. Detected on brain astrocyte processes and astrocyte endfeet close to capillaries.
Tissue Location: Detected in brain cortex, especially around cortical blood vessels, and subjacent to pia, with lower levels in parenchymal membranes. Detected in ependymal and astroglial cells in brain. Detected in supporting Hensen's cells, inner sulcus cells and Claudius cells in the inner ear. Detected in skeletal muscle. Detected in gastric parietal cells. Detected in principal cells in collecting ducts in kidney medulla (at protein level). Detected in brain, heart and skeletal muscle.
Reconstitution and StorageStore at -20°C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4°C.
Concentration1 mg/ml
Application InfoWB: 1:100~500
IHC-P: 1:100~500
FC: 1:20~100
Gene SymbolAQP4
Gene Full Nameaquaporin 4
Alias SymbolsWCH4, aqua
NCBI Gene Id11829
Description of TargetForms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
Uniprot IDP55088
Protein Accession #NP_001295570.1
Nucleotide Accession #NM_001308641.1
Molecular Weight34 kDa
  1. What is the species homology for "AQP4 Antibody (OAAB21710)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Pig".

  2. How long will it take to receive "AQP4 Antibody (OAAB21710)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "AQP4 Antibody (OAAB21710)" provided in?

    This item is provided in "Liquid. 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "AQP4 Antibody (OAAB21710)"?

    This target may also be called "WCH4, aqua" in publications.

  5. What is the shipping cost for "AQP4 Antibody (OAAB21710)"?

    The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.

  6. What is the guarantee for "AQP4 Antibody (OAAB21710)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "AQP4 Antibody (OAAB21710)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "34 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "AQP4 Antibody (OAAB21710)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "AQP4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "AQP4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "AQP4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "AQP4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "AQP4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "AQP4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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