BAD (Ser128) Polyclonal Antibody, PE-Cy5 Conjugated

Referencia bs-0893R-PE-Cy5

embalaje : 100ul

Marca : Bioss

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BAD (Ser128) Polyclonal Antibody, PE-Cy5 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-0893R-PE-Cy5
Product Name BAD (Ser128) Polyclonal Antibody, PE-Cy5 Conjugated
Applications WB, FCM
Specificity This phophorylation site is homologous to that of Ser129 in Rat.
Reactivity Human, Mouse, Rat
Specifications
Conjugation PE-Cy5
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from mouse BAD around the phosphorylation site of Ser128
Modification Site Ser128
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 12015
Swiss Prot Q61337
Subcellular location Cytoplasm, Cell membrane
Synonyms Bbc2; AI325008; Bcl2-associated agonist of cell death; BAD; Bcl-2-binding component 6; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death; Bbc6
Background Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Application Dilution
WB 1:300-5000
FCM 1:20-100