Specifications

Product Data
Applications	IHC
Recommended Dilution	IHC: 100-200 Positive control: Human breast cancer Predicted cell location: Nucleus
Reactivities	Human, Mouse
Host	Rabbit
Isotype	IgG
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 2-189 amino acids of human BCL6 corepressor
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Gene Name	BCL6 corepressor
Database Link	NP_065977 Entrez Gene 71458 MouseEntrez Gene 54880 Human UniProt ID Q6W2J9
Background	The protein encoded by this gene was identified as an interacting corepressor of BCL6; a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6; but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein; which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.
Synonyms	ANOP2; FLJ20285; FLJ38041; KIAA1575; MAA2; MCOPS2; MGC71031; MGC131961
Reference Data
Protein Families	Transcription Factors