CADM1 Antibody
Referencia OACA06822-50UL
embalaje : 50ul
Marca : Aviva Systems Biology
Contact local distributor :
Teléfono : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for CADM1 Antibody (OACA06822) (OACA06822) |
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| Reference | [1]Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B)." Busam R.D., Thorsell A.G., Flores A., Hammarstrom M., Persson C., Obrink B., Hallberg B.M.J. Biol. Chem. 286:4511-4516(2011). [2]Initial characterization of the human central proteome."Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011). [3]Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins." Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D. Nat. Biotechnol. 27:378-386(2009). |
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| Predicted Species Reactivity | Human |
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | ELISA, IHC |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Cell adhesion molecule 1 protein (45-344AA) |
| Purification | Affinity Purified |
| Concentration | Varies by lot. See vial for concentration. |
| Application Info | IHC: 1:20~200 |
| Gene Symbol | CADM1 |
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| Gene Full Name | cell adhesion molecule 1 |
| Alias Symbols | BL2;cell adhesion molecule 1;IGSF4;IGSF4A;immunoglobulin superfamily member 4;immunoglobulin superfamily, member 4D variant 1;immunoglobulin superfamily, member 4D variant 2;Necl-2;NECL2;nectin-like 2;nectin-like protein 2;RA175;sgIGSF;spermatogenic immunoglobulin superfamily;ST17;sTSLC-1;synaptic cell adhesion molecule;SYNCAM;synCAM1;truncated CADM1 protein;TSLC1;TSLC-1;TSLC1/Nectin-like 2/IGSF4;tumor suppressor in lung cancer 1. |
| NCBI Gene Id | 23705 |
| Protein Name | Cell adhesion molecule 1 |
| Description of Target | Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa. |
| Uniprot ID | Q9BY67 |
| Protein Accession # | NP_001091987 |
| Nucleotide Accession # | NM_001098517 |
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What is the species homology for "CADM1 Antibody (OACA06822)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "CADM1 Antibody (OACA06822)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "CADM1 Antibody (OACA06822)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CADM1 Antibody (OACA06822)"?
This target may also be called "BL2;cell adhesion molecule 1;IGSF4;IGSF4A;immunoglobulin superfamily member 4;immunoglobulin superfamily, member 4D variant 1;immunoglobulin superfamily, member 4D variant 2;Necl-2;NECL2;nectin-like 2;nectin-like protein 2;RA175;sgIGSF;spermatogenic immunoglobulin superfamily;ST17;sTSLC-1;synaptic cell adhesion molecule;SYNCAM;synCAM1;truncated CADM1 protein;TSLC1;TSLC-1;TSLC1/Nectin-like 2/IGSF4;tumor suppressor in lung cancer 1." in publications.
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What is the shipping cost for "CADM1 Antibody (OACA06822)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
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What is the guarantee for "CADM1 Antibody (OACA06822)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CADM1 Antibody (OACA06822)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CADM1 Antibody (OACA06822)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CADM1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CADM1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CADM1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CADM1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CADM1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CADM1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.