CD21 Mouse Monoclonal Antibody [Clone ID: CA2.1D6]

Referencia AM05866RP-N

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CD21 Mouse Monoclonal Antibody [Clone ID: CA2.1D6]

Specifications
Product Data
Clone Name CA2.1D6
Application FC
Application Flow Cytometry.
Reactivity Canine, Equine, Feline
Antibody Host Mouse
Clonality Monoclonal
Specificity This antibody recognises CD21, a cell surface antigen expressed by canine B lymphocytes.
Buffer Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide, 1% Bovine Serum Albumin
Label: PE
State: Lyophilised purified IgG
Label: R. Phycoerythrin (RPE)
Reconstitution Method Reconstitute with 1 ml distilled water
Purification Affinity chromatography on Protein G
Conjugation PE
Storage Prior to and following reconstitution store the antibody at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Database Link
Background CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.
Synonyms Complement receptor type 2, CR2, C3DR, C3d receptor, EBV Receptor, Dendritic Cell Marker
Reference Data
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