CEA antibody [Col-1]
Referencia GTX17254-1ml
embalaje : 1ml
Marca : Genetex
Contact local distributor :
Teléfono : +1 850 650 7790
![Anti-CD66e antibody[Col-1] used in IHC (Paraffin sections) (IHC-P). GTX17254](http://www.genetex.com/templates/default/js/lightbox/images/loading.gif "Anti-CD66e antibody[Col-1] used in IHC (Paraffin sections) (IHC-P). GTX17254")
Host | Mouse |
|---|---|
Clonality | Monoclonal |
Clone Name | Col-1 |
Isotype | IgG2a |
Application | ICC/IF, IHC-P |
Reactivity | Human |
| Package | 1 ml |
Datasheet File View product citations for antibody GTX17254 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application | Recommended Dilution |
|---|---|
| ICC/IF | Assay dependent |
| IHC-P | 1:75-1:100 |
Not tested in other applications.
Calculated MW
77 kDa. ( Note )
Product Note
This antibody stains specific regions of CEA. It reacts with colorectal adenocarcinomas but does not show any staining with polymorphonuclear neutrophils and erythrocytes.
PROPERTIES
Form
Liquid
Buffer
Tissue culture supernatant
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Antigen Species
Human
Immunogen
BALB/C mice were injected with extract of colon carcinoma cells.
Purification
Unpurified
Conjugation
Unconjugated
RRID
AB_422654
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
carcinoembryonic antigen related cell adhesion molecule 5 , CD66e , CEA
Cellular Localization
Cell membrane , Apical cell membrane , Cell surface
Background
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Database
DATA IMAGES
| | GTX17254 IHC-P ImageIHC-P analysis of human colon carcinoma tissue using GTX17254 CEA antibody [Col-1]. |
Application Reference
Tomoaki Furuta et al. Cancer Sci 2021; 112 (9) : 3722-3731 Carcinoembryonic antigen as a specific glycoprotein ligand of rBC2LCN lectin on pancreatic ductal adenocarcinoma cells.
Application : ICC/IF, IHC-P
Stiekema A et al. Cancer 2017; 125 (3) : 197-204 Human epididymis protein 4 immunostaining of malignant ascites differentiates cancer of Mullerian origin from gastrointestinal cancer.
Application : IHC-P
REVIEW
Application Reference
Tomoaki Furuta et al. Cancer Sci 2021; 112 (9):3722-3731 Carcinoembryonic antigen as a specific glycoprotein ligand of rBC2LCN lectin on pancreatic ductal adenocarcinoma cells.
Application : ICC/IF, IHC-P
Stiekema A et al. Cancer 2017; 125 (3):197-204 Human epididymis protein 4 immunostaining of malignant ascites differentiates cancer of Mullerian origin from gastrointestinal cancer.
Application : IHC-P
| SDS | |
|---|---|
| Sodium Azide.pdf | |
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