DNASE1L3, NT (DNASE1L3, DHP2, DNAS1L3, Deoxyribonuclease gamma, DNase I homolog protein DHP2, Deoxyribonuclease I-like 3, Liver and spleen DNase) (Azide free) (HRP)

Referencia 034730-HRP-200ul

embalaje : 200ul

Marca : US Biological

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Teléfono : +1 850 650 7790


034730-HRP Rabbit Anti-DNASE1L3, NT (DNASE1L3, DHP2, DNAS1L3, Deoxyribonuclease gamma, DNase I homolog protein DHP2, Deoxyribonuclease I-like 3, Liver and spleen DNase) (Azide free) (HRP)

Clone Type
Polyclonal
Host
rabbit
Swiss Prot
Q13609
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Rt
Accession #
NP_004935.1; Q13609
Gene #
DNASE1L3
Shipping Temp
Blue Ice
Storage Temp
-20°C

This gene encodes a member of the DNase family. The protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.||Applications:|Suitable for use in Western Blot and ELISA. Other applications not tested.||Recommended Dilutions:|Optimal dilutions to be determined by the researcher.||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. ||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Concentration: As Reported|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish peroxidase (HRP).|Purity: Purified by Protein A and peptide affinity chromatography.|Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 14-43 in the N-terminal region of human DNASE1L3.|Specificity: Recognizes DNASE1L3. Species Crossreactivity: rat.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 14-43 in the N-terminal region of human DNASE1L3.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish peroxidase (HRP).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes DNASE1L3. Species Crossreactivity: rat.
References
1. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) 2. Ueki, M., et al. Clin. Chim. Acta 407 (1-2), 20-24 (2009) 3. Mizuta, R., et al. Biomed. Res. 30(3):165-170(2009) 4. Boulares, H., et al. Biochem. Biophys. Res. Commun. 341(2):653-662(2006) 5. Okamoto, M., et al. Biochem. Biophys. Res. Commun. 327(1):76-83(2005)

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