ErbB3 (ERBB3, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 avian, HGNC:3431, ErbB-3, HER3, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3) (BSA & Azide Free) (APC)

Referencia E3451-35DX-APC-100ul

embalaje : 100ul

Marca : US Biological

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E3451-35DX-APC ErbB3 (ERBB3, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 avian, HGNC:3431, ErbB-3, HER3, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3) (BSA & Azide Free) (APC) discontinued

Clone Type
Polyclonal
Host
mouse
Source
rat
Isotype
IgG1
Grade
Affinity Purified
Applications
IP WB
Crossreactivity
Hu Mo Rt
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze

c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. c-erbB-3 is over-expressed in a variety of tumors including breast, stomach, pancreas, and colon. Heregulin & EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents. ||Applications:|Suitable for use in Immunoprecipitation and Western Blot.|Other applications not tested.||Recommended Dilution: |Optimal dilution to be determined by researcher.||Positive Control: |T47D or MAD 109 cells. ||Storage and Stability:|Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. ||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG1|Clone No: 3F164 (2B5)|Host: mouse|Source: rat|Concentration: As Reported |Form: Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).|Purity: Purified by Protein G affinity chromatography.|Immunogen: Recombinant protein corresponding to aa1234-1259 from rat c-erbB-3/HER-3 oncoprotein. MW of Antigen: 185kD. Cellular Localization: Cytoplasmic and cell membrane.|Specificity: Recognizes rat ErbB3. Species Crossreactivity: human and mouse.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Recombinant protein corresponding to aa1234-1259 from rat c-erbB-3/HER-3 oncoprotein. MW of Antigen: 185kD. Cellular Localization: Cytoplasmic and cell membrane.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes rat ErbB3. Species Crossreactivity: human and mouse.
References
1. Prigent SA and Lemoine NR. (1992) Progress in Growth Factor Research 4:1–24. 2. Plowman GD, et al. (1993) Proc Natl Acad Sci USA 90:1746–50. 3. Krauss MH, et al. (1989) Proc Natl Acad Sci USA 86:9193–7.