Specifications

Product Data
Applications	IHC
Recommended Dilution	IHC: 100-300 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm
Reactivities	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
Clonality	Polyclonal
Immunogen	Full length fusion protein
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Gene Name	ferritin heavy chain 1
Database Link	NP_002023 Entrez Gene 14319 MouseEntrez Gene 25319 RatEntrez Gene 2495 Human UniProt ID P02794
Background	This gene encodes the heavy subunit of ferritin; the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed; but their biological validity has not been determined.
Synonyms	FHC; FTH; FTHL6; HFE5; PIG15; PLIF
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Porphyrin and chlorophyll metabolism