Fibroblast Growth Factor Receptor beta (Flg, FGFRb, FGFR1) (APC)
Referencia F4305-08-APC-100ul
embalaje : 100ul
Marca : US Biological
F4305-08-APC Fibroblast Growth Factor Receptor beta (Flg, FGFRb, FGFR1) (APC)
Clone Type
PolyclonalHost
mouseSource
bovineIsotype
IgG1Grade
Affinity PurifiedApplications
FC FLISA IHC IP WBCrossreactivity
Bo Ch Gp Hu Mo RtShipping Temp
Blue IceStorage Temp
4°C Do Not FreezeCurrently four FGF receptors have been identified, FGFR-1 (flg), FGFR-2 (bek), FGFR-3, and FGFR-4. FGFR-1 and FGFR-2 exist in multiple forms that represent alternative splicing of their respective genes. The FGF Receptor consists of three immunoglobulin-like domains, a transmembrane region and a cytosolic tyrosine kinase domain which is activated by ligand binding. FGFs play important roles in angiogenesis, wound healing, tumorigenesis and metastasis. The FGF family consists of 7 members, FGF-1 through FGF-7. FGFs 1 and 2 are also known as basic FGF (bFGF) and acidic FGF (aFGF), respectively. It is known that multiple FGFs can bind and activate FGFR-1, FGFR-2, and FGFR-3. ||Applications: |Suitable for use in FLISA, Western Blot, Immunoprecipitation, Flow Cytometry and Immunohistochemistry. Other applications not tested.||Recommended Dilutions:|Immunohistochemistry: Paraffin sections|Optimal dilutions to be determined by the researcher.||Hybridoma: |Sp2/0/Ag14 myeloma cells with spleen cells from Balb/c mice. ||Storage and Stability:|Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.||Note: Applications are based on unconjugated antibody.