Human alpha Glucosidase II (GANAB) activation kit by CRISPRa
Referencia GA108112
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Human alpha Glucosidase II (GANAB) activation kit by CRISPRa
SKU
GA108112
GANAB CRISPRa kit - CRISPR gene activation of human glucosidase II alpha subunit
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | GANAB |
| Locus ID | 23193 |
| Components | GA108112G1, alpha Glucosidase II gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108112G2, alpha Glucosidase II gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108112G3, alpha Glucosidase II gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001278192, NM_001278193, NM_001278194, NM_001329222, NM_001329223, NM_001329224, NM_001329225, NM_014610, NM_198334, NM_198335 |
| UniProt ID | Q14697 |
| Synonyms | G2AN; GIIA; GLUII; PKD3 |
| Summary | This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN418899 | GANAB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.