Human Aminopeptidase A (ENPEP) activation kit by CRISPRa
Referencia GA101409
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Human Aminopeptidase A (ENPEP) activation kit by CRISPRa
SKU
GA101409
ENPEP CRISPRa kit - CRISPR gene activation of human glutamyl aminopeptidase
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | ENPEP |
| Locus ID | 2028 |
| Components | GA101409G1, Aminopeptidase A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101409G2, Aminopeptidase A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101409G3, Aminopeptidase A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001977 |
| UniProt ID | Q07075 |
| Synonyms | APA; CD249; gp160 |
| Summary | The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can regulate blood vessel formation and enhance tumorigenesis in some tissues. Along with ANPEP and DPP4, ENPEP was found to be a candidate co-receptor for the coronavirus SARS-CoV-2, which causes COVID-19. [provided by RefSeq, Apr 2020] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN410521 | ENPEP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.