Human Dehydrodolichyl Diphosphate Synthase (DHDDS) activation kit by CRISPRa

Referencia GA112748

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Human Dehydrodolichyl Diphosphate Synthase (DHDDS) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DHDDS
Locus ID 79947
Components

GA112748G1, Dehydrodolichyl Diphosphate Synthase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112748G2, Dehydrodolichyl Diphosphate Synthase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112748G3, Dehydrodolichyl Diphosphate Synthase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001243564, NM_001243565, NM_001319959, NM_024887, NM_205861
UniProt ID Q86SQ9
Synonyms CIT; CPT; DS; HDS; RP59
Summary The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
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SKU Description Size
KN401430 DHDDS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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