Human IL-13 ELISpot Pair, 10 x 96-well
Product Images
Specifications
| Product Data | |
| Format | 10 x 96-well |
| Assay Type | Enzyme-Linked ImmunoSpot (ELISpot) |
| Signal | Colorimetric |
| Specificity | Recognizes both natural and recombinant human IL-13 |
| Cross Reactivity | No cross reactivity with other human cytokines |
| Components | ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples. |
| Background | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] |
| Gene Symbol | IL13 |
| Gene ID | 3596 |
Documents
| SDS |