Human Proteasome subunit beta type 2 (PSMB2) activation kit by CRISPRa
Referencia GA103859
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Human Proteasome subunit beta type 2 (PSMB2) activation kit by CRISPRa
SKU
GA103859
PSMB2 CRISPRa kit - CRISPR gene activation of human proteasome subunit beta 2
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | PSMB2 |
| Locus ID | 5690 |
| Components | GA103859G1, Proteasome subunit beta type 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103859G2, Proteasome subunit beta type 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103859G3, Proteasome subunit beta type 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001199779, NM_001199780, NM_002794 |
| UniProt ID | P49721 |
| Synonyms | HC7-I |
| Summary | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN410452 | PSMB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.