Human TNF-R1
Referencia 600299
embalaje : 0.01mg
Marca : Abbiotec
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Teléfono : +1 850 650 7790
Description
Two types of soluble TNF receptors (sTNF-R1 and sTNF-R2) have been identified which act to neutralize the biological activities of TNF alpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Elevated levels of soluble TNF receptors have been found in the amniotic fluid of pregnant women. Recombinant sTNF-R1 comprises a 161 amino acid fragment (41-201) corresponding to the mature TNF-R1 protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
Each vial contains 0.01 mg protein (liquid) in PBS pH7.4, 50% glycerol. Final concentration 0.1-1 mg/ml.
Alternate Names
TNF-R1; Soluble tumour necrosis factor receptor-1; TNF-R1 Tumour necrosis factor receptor subfamily member 1A (TNFRSF1A); Tumour necrosis factor binding protein I (TNFBPI); Tumour necrosis factor receptor type I (TNFRI); Tumour necrosis factor-alpha receptor (TNFAR); CD120a antigen; p55; p55-R; p60; MGC19588
Accession No.
MW
22.68 kDa
Sequence
His-Tag sequence not included: DSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTD CRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN QYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECV SCSNCKKSLECTKLCLPQIEN
Source
E. coli
Purity
Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
Storage
Store at -20°C. Product is guaranteed one year from the date of shipment.
For research use only, not for diagnostic or therapeutic procedures.