Human Xanthine Oxidase (XDH) activation kit by CRISPRa
Referencia GA105165
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Human Xanthine Oxidase (XDH) activation kit by CRISPRa
SKU
GA105165
XDH CRISPRa kit - CRISPR gene activation of human xanthine dehydrogenase
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | XDH |
| Locus ID | 7498 |
| Components | GA105165G1, Xanthine Oxidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105165G2, Xanthine Oxidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105165G3, Xanthine Oxidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_000379 |
| UniProt ID | P47989 |
| Synonyms | XAN1; XO; XOR |
| Summary | Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN419402 | XDH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.