Interferon alpha (IFN alpha) Rabbit Polyclonal Antibody
Referencia SP2126A
embalaje : 500ug
Product Data | |
Application | ELISA, FN, IP, WB |
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Application | ELISA. Western Blot: This antibody cross reacts with IFN beta in western blots but does not show any cross reactivity with IFN gamma; this antibdoy detects a band of approximately 19kDa. Functional Assays. Immunoprecipitation. |
Reactivity | Chicken |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant chicken Interferon alpha. |
Specificity | This antibody recognizes Interferon alpha (chIFN-alpha). In bioassays, this antiserum neutralizes chIFN-alpha, but not chIFN-beta, and can therefore be used to discriminate IFN alpha and IFN beta bioactivities. Product SA027 is the immunogen used to produce this antibody. |
Buffer | PBS State: Azide Free State: Liquid purified IgG Stabilizer: None Preservative: None |
Concentration | lot specific |
Purification | Affinity chromatography on protein G |
Conjugation | Unconjugated |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Background | The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. |
Synonyms | B Cell Interferon, IFN-alpha, IFNA, Interferon-alpha, Leukocyte Interferon, Type I Interferon |
Reference Data |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.