Interleukin 2, Recombinant, Mouse (Interleukin-2, IL-2, IL2, T-cell Growth Factor, TCGF)

Referencia I7663-27T-50ug

embalaje : 50ug

Marca : US Biological

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I7663-27T Interleukin 2, Recombinant, Mouse (Interleukin-2, IL-2, IL2, T-cell Growth Factor, TCGF)

Clone Type
Polyclonal
Swiss Prot
P04351
Grade
Highly Purified
Shipping Temp
Blue Ice
Storage Temp
-20°C

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. ||Recombinant mouse IL-2 is a 17.2kD protein containing 148 amino acid residues, expressed in E. coli.||Amino Acid Sequence:|PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ||Biological Activity: |The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.2ng/ml, corresponding to a specific activity of ≥5x10e6 units/mg.||Applications:|Suitable for use in Functional Assays. Other applications not tested. ||Recommended Dilution:|Optimal dilutions to be determined by the researcher. ||Storage and Stability:|Lyophilized and reconstituted products may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Applications
Source: Recombinant, E. coli|Purity: ≥98% (SDS PAGE, HPLC). Endotoxin: ≤0.1ng/ug (<1EU/ug)|Concentration: ~0.1mg/ml (after reconstitution) |Form: Supplied as a lyophilized powder (film) in 10mM sodium citrate, pH 4.0. Preservative free. Reconstitute with sterile dH2O to 0.1-1mg/ml.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Form
Supplied as a lyophilized powder (film) in 10mM sodium citrate, pH 4.0. Preservative free. Reconstitute with sterile dH2O to 0.1-1mg/ml.
Purity
≥98% (SDS PAGE, HPLC). Endotoxin: ≤0.1ng/ug (<1EU/ug)