• Specifications

    Product Description

    Rabbit polyclonal antibody raised against synthetic peptide of KCNK2.

    Immunogen

    A synthetic peptide corresponding to amino acids 1-100 of human KCNK2.

    Host

    Rabbit

    Reactivity

    Human

    Specificity

    88% sequence identity with rat protein. TREK 1 Please note that it is essential to run against membrane preps. NOT recommended for immunohistochemistry.

    Form

    Liquid

    Conjugation

    DyLight 488

    Recommend Usage

    Western Blot (2 ug/ mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In 50 mM sodium borate

    Storage Instruction

    Store at 4°C. Do not freeze.

  • Applications

    Western Blot

  • Gene Info — KCNK2

    Entrez GeneID

    3776

    Protein Accession#

    O95069

    Gene Name

    KCNK2

    Gene Alias

    K2p2.1, MGC126742, MGC126744, TPKC1, TREK, TREK-1, TREK1, hTREK-1c, hTREK-1e

    Gene Description

    potassium channel, subfamily K, member 2

    Omim ID

    603219

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    K2P2.1 potassium channel|OTTHUMP00000035062|OTTHUMP00000035063|TWIK-related potassium channel 1|potassium inwardly-rectifying channel, subfamily K, member 2|tandem-pore-domain potassium channel TREK-1|two-pore potassium channel 1

  • Diseases