LDN-192960 2HCl [184582-62-5]

Referencia AOB1696-100

embalaje : 100mg

Marca : AOBIOUS

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LDN-192960 dihydrochloride

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Data sheet

Molecular FormulaC18H22Cl2N2O2S
Molecular Weight401.35
CAS Numbers184582-62-5 (free base)
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymLDN-192960 HCl; LDN-192960 hydrochloride; LDN 192960; LDN192960; LDN-192960;
IUPAC/Chemical Name3-(2,7-Dimethoxy-acridin-9-ylsulfanyl)-propylamine dihydrochloride
InChl KeyFNHCUCJBABESJB-UHFFFAOYSA-N
InChl CodeInChI=1S/C18H20N2O2S.2ClH/c1-21-12-4-6-16-14(10-12)18(23-9-3-8-19)15-11-13(22-2)5-7-17(15)20-16;;/h4-7,10-11H,3,8-9,19H2,1-2H3;2*1H
SMILES CodeNCCCSC1=C(C=C(OC)C=C2)C2=NC3=CC=C(OC)C=C31.00Cl.00Cl
References1) Cuny GD, et al. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3491-4.

2) Katrin Kestav, et al. Structure, Roles and Inhibitors of a Mitotic Protein Kinase Haspin. Curr Med Chem. 2017;24(21):2276-2293.

More info

Potent and selective haspin inhibitor

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Referencia
Descripción
Cond.
Precio Sin IVA
A21546-50
 50mg 
A21546-100
 100mg