Mouse Anti-Feline CD4-FITC
Referencia 8130-02
embalaje : 0.5mg
Marca : Southern Biotech
Contact local distributor :
Teléfono : +1 850 650 7790
| Clone | 3-4F4 |
|---|---|
| Isotype | Mouse IgG1κ |
| Isotype Control | Mouse IgG1-FITC (15H6) |
| Specificity | Feline/Lion CD4 |
| Alternative Names | fCD4 |
| Description | Feline CD4, a member of the immunoglobulin superfamily of cell surface receptors, is a type I transmembrane glycoprotein that is expressed on the helper/inducer subpopulation of peripheral T lymphocytes. It is present on approximately 55% of thymocytes, 15% of splenocytes, 40% of lymph node cells, and 25% of peripheral blood lymphocytes. CD4 functions as an accessory molecule in the recognition of foreign antigens in association with MHC Class II antigens by T cells. |
| Immunogen | Feline T cells |
| Conjugate | FITC (Fluorescein) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C; Avoid exposure to light |
| Applications | Flow Cytometry – Quality tested 1,4,7-31 Immunohistochemistry-Frozen Sections – Reported in literature 3-5 Immunocytochemistry – Reported in literature 2 Immunoprecipitation – Reported in literature 1,2 Separation – Reported in literature 6 Blocking – Reported in literature 1 |
| RRID Number | AB_2796414 |
| Gene ID | 493775 (Feline) |
| Gene ID Symbol | CD4 (Feline) |
| UniProt ID | P79355 (Feline |
| UniProt Name | P79355_FELCA (Feline) |
Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup
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- 1. Ackley CD, Hoover EA, Cooper MD. Identification of a CD4 homologue in the cat. Tissue Antigens. 1990;35:92-8. (Immunogen, FC, IP, Block)
- 2. Shimojima M, Morikawa S, Maeda K, Tohya Y, Miyazawa T, Mikami T. Generation of monoclonal antibodies against a feline CD antigen (CD4) expressed by a recombinant baculovirus. J Vet Med Sci. 1997;59:467-9. (IP, ICC)
- 3. Rideout BA, Lowenstine LJ, Hutson CA, Moore PF, Pedersen NC. Characterization of morphologic changes and lymphocyte subset distribution in lymph nodes from cats with naturally acquired feline immunodeficiency virus infection. Vet Pathol. 1992;29:391-9. (IHC-FS)
- 4. Femenia F, Crespeau F, Fontaine JJ, Boucheix C, Parodi AL. Early haematological and pathological abnormalities of pathogen-free cats experimentally infected with feline immunodeficiency virus (FIV). Vet Res. 1994;25:544-54. (IHC-FS, FC)
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- 8. Hohdatsu T, Hirabayashi H, Motokawa K, Koyama H. Comparative study of the cell tropism of feline immunodeficiency virus isolates of subtypes A, B and D classified on the basis of the env gene V3-V5 sequence. J Gen Virol. 1996;77:93-100. (FC)
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