Mouse Anti-Human CD42b-LE/AF

Referencia 9615-14

embalaje : 0.5mg

Marca : Southern Biotech

Contact local distributor :


Teléfono : +1 850 650 7790

More Information
Clone MM2/174
Isotype Mouse IgG1κ
Isotype Control Mouse IgG1-LE/AF (15H6)
Specificity Human CD42b
Alternative Names GPIbα, glycocalicin
Description CD42b, also known as GPIbα, is a two-chain membrane glycoprotein that forms a noncovalent complex with CD42a (GPIX) on the surface of platelets and megakaryocytes. Binding of the GPIb/GPIX heterodimer to von Willebrand factor bound to exposed subendothelial surfaces is essential for platelet adhesion at sites of injury.
Immunogen Human plasma membrane
Conjugate LE/AF (Low Endotoxin/Azide Free)
Buffer Formulation Phosphate buffered saline, pH 7.4
Clonality Monoclonal
Concentration 0.5 mg/mL
Volume 1.0 mL
Recommended Storage 2-8°C; Handle under aseptic conditions
Applications Flow Cytometry – Quality tested 5,6
Immunohistochemistry-Frozen Sections – Reported in literature 2
Immunohistochemistry-Paraffin Sections – Reported in literature 3,4
Immunocytochemistry – Reported in literature 2
Immunoprecipitation – Reported in literature 1
Western Blot – Reported in literature 3

RRID Number AB_2797006
Gene ID 2811 (Human)
Gene ID Symbol GP1BA (Human)
Gene ID Aliases BDPLT1; BDPLT3; BSS; CD42B; CD42b-alpha; DBPLT3; GP1B; GPIbA; GPIbalpha; VWDP
UniProt ID P07359 (Human
UniProt Name GP1BA_HUMAN (Human)
Documentation
Technical Bulletin Safety Datasheet

Certificate of Analysis Lookup

Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view

  1. 1. Yajima A, Takahashi Y, Konishi K. Identification of platelet receptors for the Streptococcus gordonii DL1 sialic acid-binding adhesin. Microbiol Immunol. 2005;49:795-800. (IP)
  2. 2. Parravicini CL, Soligo D, Berti E, Cattoretti G, Gaiera G, Vago L. Immunohistochemical reactivity of anti-platelet mAb in normal human tissues and bone marrow. In: Knapp W, Dörken B, Gilks WR, Rieber EP, Schmidt RE, Stein H, et al, editors. Leukocyte Typing IV: White Cell Differentiation Antigens. Oxford: Oxford University Press; 1989. p. 981-5. (IHC-FS, ICC)
  3. 3. Mäyränpää MI, Reséndiz JC, Heikkilä HM, Lindstedt KA, Kovanen PT. Improved identification of endothelial erosion by simultaneous detection of endothelial cells (CD31/CD34) and platelets (CD42b). Endothelium. 2007;14:81-7. (WB, IHC-PS)
  4. 4. Ishigaki H, Miyauchi J, Yokoe A, Nakayama M, Yanagi T, Taga T, et al. Expression of megakaryocytic and myeloid markers in blasts of transient abnormal myelopoiesis in a stillbirth with Down syndrome: report of histopathological findings of an autopsy case. Hum Pathol. 2011;42:141-5. (IHC-PS)
  5. 5. Zamai L, Secchiero P, Pierpaoli S, Bassini A, Papa S, Alnemri ES, et al. TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesis. Blood. 2000;95:3716-24. (FC)
  6. 6. Heindl B, Zahler S, Welsch U, Becker BF. Disparate effects of adhesion and degranulation of platelets on myocardial and coronary function in postischaemic hearts. Cardiovasc Res. 1998;38:383-94. (FC)

Usted podría estar interesado también en los siguientes productos:



Referencia
Descripción
Cond.
Precio Sin IVA
orb387888-100ug
 100ug 
9615-01
 0.1mg