Mouse Vldlr activation kit by CRISPRa
Referencia GA204604
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Mouse Vldlr activation kit by CRISPRa
SKU
GA204604
Vldlr CRISPRa kit - CRISPR gene activation of mouse very low density lipoprotein receptor
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Vldlr |
| Locus ID | 22359 |
| Components | GA204604G1, Vldlr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204604G2, Vldlr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204604G3, Vldlr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001161420, NM_001347441, NM_013703 |
| UniProt ID | P98156 |
| Synonyms | AA408956; AI451093; AW047288 |
| Summary | Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.[UniProtKB/Swiss-Prot Function] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN518900 | Vldlr - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.