NOS2 (C-11)
Referencia sc-7271
embalaje : 200µg/ml
Marca : Santa Cruz Biotechnology
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Anticorps iNOS (C-11): sc-7271
- L'anticorps iNOS C-11 est un monoclonal IgG1 κ L'Anticorps iNOS, cité dans 582 publications, fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 1126-1144 près de C-terminus de NOS2 d'origine mouse
- L'Anticorps iNOS (C-11) est recommandé pour la détection de NOS2 (iNOS) d'origine mouse, rat et human par WB, IP, IF, IHC(P), FCM et ELISA
- Anti-L'Anticorps iNOS (C-11) est disponible conjugué à l'agarose pour IP; à l'HRP pour WB, IHC(P) et ELISA; et soit à la phycoerythrin ou FITC pour IF, IHC(P) et FCM
- aussi disponible conjugué à l'Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 ou Alexa Fluor® 647 pour WB (RGB), IF, IHC(P) et FCM
- aussi disponible conjugué à l'Alexa Fluor® 680 ou Alexa Fluor® 790 pour WB (NIR), IF et FCM
- aussi disponible conjugué soit au TRITC soit à l'Alexa Fluor® 405 pour IF, IHC(P) et FCM
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps iNOS (C-11) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps iNOS (C-11) ().
ACCÈS RAPIDE AUX LIENS
, NOS2, NOS3 et pan NOS
NOS2 Antibody (C-11) is an IgG1 κ mouse monoclonal NOS2 antibody (also designated iNOS antibody or NOS2A antibody) that detects the NOS2 protein of mouse, rat and human origin by WB, IP, IF, IHC(P), FCM and ELISA. NOS2 Antibody (C-11) is available as both the non-conjugated anti-NOS2 antibody form, as well as multiple conjugated forms of anti-NOS2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Nitric oxide (NO) has a broad range of biological activities and has been implicated in signaling pathways in phylogenetically diverse species. Nitric oxide synthases (NOSs), the enzymes responsible for synthesis of NO, contain an N-terminal oxygenase domain and a C-terminal reductase domain. NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells. The inducible form of NOS, NOS2 (also designated iNOS), is Ca2+-independent and is expressed in a broad range of cell types.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
References:
- Epithelial autotoxicity of nitric oxide: role in the respiratory cytopathology of pertussis. | Heiss, LN., et al. 1994. Proc Natl Acad Sci U S A. 91: 267-70. PMID: 7506415
- Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. | Kamijo, R., et al. 1994. Science. 263: 1612-5. PMID: 7510419
- Nitric oxide synthases: roles, tolls, and controls. | Nathan, C. and Xie, QW. 1994. Cell. 78: 915-8. PMID: 7522969
- Nitric oxide synthase: aspects concerning structure and catalysis. | Marletta, MA. 1994. Cell. 78: 927-30. PMID: 7522970
- Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease. | Bukrinsky, MI., et al. 1995. J Exp Med. 181: 735-45. PMID: 7530762
- NO at work. | Schmidt, HH. and Walter, U. 1994. Cell. 78: 919-25. PMID: 7923361
- Nitric oxide is an important mediator for tumoricidal activity in vivo. | Farias-Eisner, R., et al. 1994. Proc Natl Acad Sci U S A. 91: 9407-11. PMID: 7937779
Espèces | Nom du Gène | Gene ID | Localisation chromosomique | Numéro d'accession de l'isoforme (ARNm) | Numéro d'accès aux protéines | Numéro OMIM™ |
---|---|---|---|---|---|---|
Human | NOS2 | Entrez Gene ID: 4843 | 17q11.2 | XM_011524859, XM_011524860, XM_011524861, XM_011524862, NM_000625, NM_153292 | UniProt ID: P35228 | 611162 |
Mouse | Nos2 | Entrez Gene ID: 18126 | 11 B5 | XM_006532446, NM_001313921, NM_001313922, NM_010927 | UniProt ID: P29477 | N/A |
Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz® conjugates which eliminates the need for a secondary antibody.
Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-iNOS Antibody (C-11) has 582 citations in a variety of scientific publications.
Primary antibodies like Anti-iNOS Antibody (C-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.
L'anticorps pan NOS préféré est l'Anticorps pan NOS (NOS-3F7-B11 B5): sc-58399.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps iNOS (C-11) | sc-7271 | 200 µg/ml | .00 | |||
iNOS (C-11): m-IgG Fc BP-HRP Kit | sc-526492 | 200 µg Ab; 10 µg BP | .00 | |||
iNOS (C-11): m-IgG1 BP-HRP Kit | sc-531865 | 200 µg Ab; 20 µg BP | .00 | |||
Anticorps iNOS (C-11) AC | sc-7271 AC | 500 µg/ml, 25% agarose | .00 | |||
Anticorps iNOS (C-11) HRP | sc-7271 HRP | 200 µg/ml | .00 | |||
Anticorps iNOS (C-11) FITC | sc-7271 FITC | 200 µg/ml | .00 | |||
Anticorps iNOS (C-11) PE | sc-7271 PE | 200 µg/ml | .00 | |||
Anticorps iNOS (C-11) Alexa Fluor® 488 | sc-7271 AF488 | 200 µg/ml | .00 | |||
Anticorps iNOS (C-11) Alexa Fluor® 546 | sc-7271 AF546 | 200 µg/ml | .00 | |||
Anticorps iNOS (C-11) Alexa Fluor® 594 | sc-7271 AF594 | 200 µg/ml | .00 | |||
Anticorps iNOS (C-11) Alexa Fluor® 647 | sc-7271 AF647 | 200 µg/ml | .00 | |||
Anticorps iNOS (C-11) Alexa Fluor® 680 | sc-7271 AF680 | 200 µg/ml | .00 | |||
Anticorps iNOS (C-11) Alexa Fluor® 790 | sc-7271 AF790 | 200 µg/ml | .00 | |||
Anticorps iNOS (C-11) TRITC | sc-7271 TRITC | 200 µg/ml | .00 | |||
Anticorps iNOS (C-11) Alexa Fluor® 405 | sc-7271 AF405 | 200 µg/ml | .00 | |||
iNOS (C-11) peptide neutralisant | sc-7271 P | 100 µg/0.5 ml | .00 |
Nos2内皮功能是什么
Is this antibody possible for iNOS detection using IHC-F staning?
This NOS2 antibody is a mouse antibody, and it's also recommended for mouse IHC detection, the question is what secondary antibody should I choose for the detection?
The host species is mouse, correct?
Hi, can this antibody be use on rat's retina in iNOS detection using IHC staning?
How specific is NOS2 (c-11) for Rat. I would like to try it for iNOS detection in rat brain tissue. Please provide me any information related to this. I will highly appreciate your quickest response.
Welcher Clon verbirgt sich hinter dem Antikörper NOS2 (C-11) (Bestell-Nr.: sc-7271 AF647)?
Dose it work well in rat brain tissue for IF?
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