POU5F1 Antibody - N-terminal region : FITC
Referencia P100956_T100-FITC
embalaje : 100ul
Marca : Aviva Systems Biology
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Teléfono : +1 850 650 7790
POU5F1 Antibody - N-terminal region (P100956_T100)
| Datasheets/Manuals | Printable datasheet for anti-POU5F1 (P100956_T100) antibody |
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| Publications | Kaeffer, B. et al. Non-invasive exploration of neonatal gastric epithelium by using exfoliated epithelial cells. PLoS One 6, e25562 (2011). 22028779 Li, Y. et al. BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a dNp63+ cytotrophoblast stem cell state. Development 140, 3965-76 (2013). 24004950 Oct-4B isoform is differentially expressed in breast cancer cells: hypermethylation of regulatory elements of Oct-4A suggests an alternative promoter and transcriptional start site for Oct-4B transcription. Biosci Rep. 31, 109-15 (2011). 20433421 |
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| Tested Species Reactivity | Human |
| Predicted Species Reactivity | Human, Dog, Goat, Pig, Rabbit |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human POU5F1 |
| Purification | Protein A purified |
| Predicted Homology Based on Immunogen Sequence | Dog: 91%; Goat: 100%; Human: 100%; Pig: 84%; Rabbit: 92% |
| Peptide Sequence | Synthetic peptide located within the following region: PCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYT |
| Concentration | 1.0 mg/ml |
| Blocking Peptide | For anti-POU5F1 (P100956_T100) antibody is Catalog # AAP31313 (Previous Catalog # AAPP02063) |
| Reference | Suo,G., et al., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1047-1051 |
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| Gene Symbol | POU5F1 |
| Gene Full Name | POU class 5 homeobox 1 |
| Alias Symbols | OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4 |
| NCBI Gene Id | 5460 |
| Protein Name | POU domain, class 5, transcription factor 1 |
| Description of Target | POU5F1 is a POU transcription factor expressed by early embryo cells and germ cells. It determines paracrine growth factor signaling from stem cells to the trophectoderm |
| Uniprot ID | Q01860 |
| Protein Accession # | NP_002692 |
| Nucleotide Accession # | NM_002701 |
| Protein Size (# AA) | 360 |
| Molecular Weight | 39kDa |
| Protein Interactions | ETS2; CETN2; XPC; RAD23B; UBC; ITCH; FOXD3; WWP2; PSMD10; NCL; PURA; PPIA; POU5F1; YBX1; KRT19; KRT14; KRT10; KRT9; KRT2; KRT1; HNRNPK; HMGB1; HIST1H1T; GAPDH; FKBP7; EHMT2; AGR2; TUBB4A; EIF5B; TUBA1A; NR2F2; TRA2B; SRSF3; RPS25; RPS23; RPS19; RPL31; RPL |
