β-Mercaptoethanol [60-24-2]
Referencia sc-202966A
embalaje : 100ml
Marca : Santa Cruz Biotechnology
Contact local distributor :
Teléfono : +1 850 650 7790
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β-Mercaptoethanol: sc-202966
β-Mercaptoethanol (CAS 60-24-2)
Noms alternatifs:
BME
Application:
β-Mercaptoethanol is a reducing agent used in electrophoresis, amino acid detection, and distinguishing ssDNA/dsDNA)
Numéro CAS:
60-24-2
Pureté:
≥99%
Masse Moléculaire:
78.10
Formule Moléculaire:
C2H6OS
Information supplémentaire:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
Pour la Recherche Uniquement. Non conforme pour le Diagnostic ou pour une Utilisation Thérapeutique.
* Consulter le Certificat d'Analyses pour les données spécifiques à un lot (incluant la teneur en eau).
ACCÈS RAPIDE AUX LIENS
Informations pour la commande
Références bibliographiques
Description
Information Technique
Données de Sécurité
SDS & Certificat d’Analyses
beta-Mercaptoethanol can act as an enzyme reactivator in systems necessitating reduction for activation, and has been used to reduce disulfide bonds in order to separate protein subunits for use in electrophoresis. This product can also be used to form o-Phthalaldehyde-beta-mercaptoethanol (OPAME), a fluorogenic reagent shown to detect amino acids based on its reaction with primary amines. More recently OPAME has been used to distinguish between ssDNA/dsDNA and even single base mismatches in the hybridization of DNA.
References:
- The activation mechanism of human porphobilinogen synthase by 2-mercaptoethanol: intrasubunit transfer of a reserve zinc ion and coordination with three cysteines in the active center. | Sawada, N., et al. 2005. J Biol Inorg Chem. 10: 199-207. PMID: 15747133
- Conformational change detection of DNA with the fluorogenic reagent of o-phthalaldehyde-beta-mercaptoethanol. | Long, YF., et al. 2008. J Phys Chem B. 112: 1783-8. PMID: 18215031
- Effect of thiol compounds on bleomycin-induced DNA and chromosome damage in human cells. | Mira, A., et al. 2013. Arch Environ Occup Health. 68: 107-16. PMID: 23428061
- Detection of plant oil DNA using high resolution melting (HRM) post PCR analysis: a tool for disclosure of olive oil adulteration. | Vietina, M., et al. 2013. Food Chem. 141: 3820-6. PMID: 23993554
- Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. | Guo, TW., et al. 2017. Cell. 171: 414-426.e12. PMID: 28985564
- Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. | Corsini, NS., et al. 2018. Cell Stem Cell. 22: 543-558.e12. PMID: 29625069
- A coculture system composed of THP-1 cells and 3D reconstructed human epidermis to assess activation of dendritic cells by sensitizing chemicals after topical exposure. | Schellenberger, MT., et al. 2019. Toxicol In Vitro. 57: 62-66. PMID: 30771472
- Stimulation of Hair Growth by Small Molecules that Activate Autophagy. | Chai, M., et al. 2019. Cell Rep. 27: 3413-3421.e3. PMID: 31216464
- Histone Modifications Regulate Chromatin Compartmentalization by Contributing to a Phase Separation Mechanism. | Wang, L., et al. 2019. Mol Cell. 76: 646-659.e6. PMID: 31543422
- SUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer. | Lopitz-Otsoa, F., et al. 2019. J Vis Exp.. PMID: 31736480
- N-glycan in the scavenger receptor cysteine-rich domain of hepsin promotes intracellular trafficking and cell surface expression. | Sun, S., et al. 2020. Int J Biol Macromol. 161: 818-827. PMID: 32553951
- Systematic Activity Maturation of a Single-Domain Antibody with Non-canonical Amino Acids through Chemical Mutagenesis. | Lindstedt, PR., et al. 2021. Cell Chem Biol. 28: 70-77.e5. PMID: 33217338
- Condensed Chromatin Behaves like a Solid on the Mesoscale InVitro and in Living Cells. | Strickfaden, H., et al. 2020. Cell. 183: 1772-1784.e13. PMID: 33326747
- SARS-CoV-2 Nsp14 activates NF- kappa B signaling and induces IL-8 upregulation. | Li, T., et al. 2021. bioRxiv.. PMID: 34075374
- Flow Cytometry-Based Determination of Ploidy from Dried Leaf Specimens in Genomically Complex Collections of the Tropical Forage Grass Urochloa s. l. | Tomaszewska, P., et al. 2021. Genes (Basel). 12: PMID: 34201593
- Jack bean urease (EC 3.5.1.5). III. The involvement of active-site nickel ion in inhibition by beta-mercaptoethanol, phosphoramidate, and fluoride. | Dixon, NE., et al. 1980. Can J Biochem. 58: 481-8. PMID: 7272836
État Physique :
Liquid
Solubilité :
Soluble in water (500 g/l), alcohol, ether, benzene, and other organic solvents.
STOCKAGE :
Store at room temperature
Point de fusion :
<-100° C
Point d'Ébullition :
157.2° C (dec.)
Densité :
1.11 g/mL at 25° C (lit.)
Indice de Réfraction :
n20D 1.50 (lit.)
Valeurs pK :
pKa: 9.64 (Predicted)
Pour la Recherche Uniquement. Non conforme pour le Diagnostic ou pour une Utilisation Thérapeutique.
WGK Allemagne :
3
RTECS :
KL5600000
PubChem CID :
1567Index Merck :
14: 5869
Numéro MDL :
MFCD00004890
Numéro CE :
200-464-6
Registre Beilstein :
773648
SMILES :
OCCS
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SAMPLE Certificate of Analysis (COA)
β-Mercaptoethanol | CAS 60-24-2 SAMPLE Certificate of AnalysisCERTIFICAT D'ANALYSE
Numéro de catalogue
Numéro de Lot
Envoyer
SAMPLE Certificate of Analysis (COA)
Catalog Number:sc-202966
Lot Number:SAMPLE
Product Name:β-Mercaptoethanol
Molecular Formula:C2H6OS
Molecular Weight:78.10
| Test | Specification | Results |
|---|---|---|
| Appearance | Clear colorless liquid | Complies |
| Identification (1H-NMR) | Consistent with structure | Complies |
| Purity (GC) | ≥ 99.0% | 99.5% |
| Purity (Titration) | ≥ 98.5% (by Na2S2O3) | 101.5% |
| Solubility | Clear colorless at 1 ml/ml in water | Complies |
| Copper | ≤ 1.0 ppm | < 0.9 ppm |
| Iron | ≤ 1.0 ppm | < 0.9 ppm |
| Lead | ≤ 5.0 ppm | < 2.6 ppm |
| Zinc | ≤ 1.0 ppm | < 0.4 ppm |
| Cell Culture Test | Complies | |
| Suitable for electrophoresis | Complies |
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
β-Mercaptoethanol, 100 ml | sc-202966A | 100 ml | .00 | |||
β-Mercaptoethanol, 250 ml | sc-202966 | 250 ml | .00 |