Anti-AKR1D1 antibody (258-308 aa)

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	AKR1D1
Gene ID:	6718
Uniprot ID:	AK1D1_HUMAN
Immunogen Region:	258-308 aa
Specificity:	This antibody detects endogenous levels of AK1D1 at Human/Mouse/Rat
Immunogen:	Synthesized peptide derived from the human AK1D1 at the amino acid range 258-308

Function	Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta-hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3-one).
Protein Name	Aldo-Keto Reductase Family 1 Member D1 3-Oxo-5-Beta-Steroid 4-Dehydrogenase Delta(4-3-Ketosteroid 5-Beta-Reductase Delta(4-3-Oxosteroid 5-Beta-Reductase
Database Links	Reactome: R-HSA-193368 Reactome: R-HSA-193775 Reactome: R-HSA-193807
Cellular Localisation	Cytoplasm
Alternative Antibody Names	Anti-Aldo-Keto Reductase Family 1 Member D1 antibody Anti-3-Oxo-5-Beta-Steroid 4-Dehydrogenase antibody Anti-Delta(4-3-Ketosteroid 5-Beta-Reductase antibody Anti-Delta(4-3-Oxosteroid 5-Beta-Reductase antibody Anti-AKR1D1 antibody Anti-SRD5B1 antibody

Information sourced from Uniprot.org

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