Anti-PAX6 antibody [1C8]

Referencia NB-22-8408

embalaje : 100µg

Marca : Neo Biotech

Contact local distributor :


Teléfono : +1 850 650 7790
Datasheet
ProductInformation

Code: NB-22-8408
ClonalityMonoclonal
Host Mouse
ReactivityHuman
ApplicationsWB, FC, ELISA
ImmunogenPurified recombinant fragment of human Pax-6 expressedin E. Coli.
ConjugationUnconjugated
GeneID5080 (Human)
DilutionrangeWB 1:500-1:2000; FC 1:200-1:400; ELISA 1:10000
SpecificityPax-6 Monoclonal Antibody detects endogenous levels ofPax-6 protein.
Swiss-ProtKeyP26367 (Human)
PurificationAffinity purification
FormAscitic fluid containing 0.03% sodium azide
ConcentrationN/A
CloneID1C8
StorageStore at -20°C. Avoid repeated freeze/thaw cycles
AlternativenamesPAX6; AN2; Paired box protein Pax-6; Aniridia type IIprotein; Oculorhombin
NoteFor research use only

General Info

Host: Mouse
Applications: WB/FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Paired box protein Pax-6 is suitable for use in Western Blot, Flow Cytometry and ELISA research applications.
Clonality: Monoclonal
Clone ID: 1C8
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
FC 1:200-1:400
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol: PAX6
Gene ID: 5080
Uniprot ID: PAX6_HUMAN
Specificity: Pax-6 Monoclonal Antibody detects endogenous levels of Pax-6 protein.
Immunogen: Purified recombinant fragment of human Pax-6 expressed in E. Coli.

Description

Post Translational Modifications Ubiquitinated by TRIM11, leading to ubiquitination and proteasomal degradation.
Function Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains. Acts as a transcriptional repressor of NFATC1-mediated gene expression.
Protein Name Paired Box Protein Pax-6
Aniridia Type Ii Protein
Oculorhombin
Database Links Reactome: R-HSA-210745
Reactome: R-HSA-381771
Reactome: R-HSA-400511
Reactome: R-HSA-5617472
Cellular Localisation Nucleus
Isoform 1: Nucleus
Isoform 5a: Nucleus
Alternative Antibody Names Anti-Paired Box Protein Pax-6 antibody
Anti-Aniridia Type Ii Protein antibody
Anti-Oculorhombin antibody
Anti-PAX6 antibody
Anti-AN2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance