Anti-Phospho-KCNA3-Tyr187 antibody (101-150 aa)

Referencia NB-22-1099-50

embalaje : 50ug

Marca : Neo Biotech

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Teléfono : +1 850 650 7790

  • Immunohistochemistry analysis of paraffin-embedded human brain, using Kv1.3/KCNA3 (Phospho-Tyr135) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from Jurkat cells treated with starved 24h, using Kv1.3/KCNA3 (Phospho-Tyr135) Antibody. The lane on the right is blocked with the phospho peptide.
  • Immunofluorescence analysis of HUVEC cells, using Kv1.3/KCNA3 (Phospho-Tyr135) Antibody. The picture on the right is blocked with the phospho peptide.

General Info

Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Potassium voltage-gated channel subfamily A member 3 channel HuKIII-Tyr187 (101-150 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol: KCNA3
Gene ID: 3738
Uniprot ID: KCNA3_HUMAN
Immunogen Region: 101-150 aa
Specificity: Phospho-Kv1.3 (Y187) Polyclonal Antibody detects endogenous levels of Kv1.3 protein only when phosphorylated at Y187.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Kv1.3/KCNA3 around the phosphorylation site of Tyr135 at the amino acid range 101-150

Description

Function Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
Protein Name Potassium Voltage-Gated Channel Subfamily A Member 3
Hgk5
Hlk3
Hpcn3
Voltage-Gated K(+ Channel Hukiii
Voltage-Gated Potassium Channel Subunit Kv1.3
Database Links Reactome: R-HSA-1296072
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Potassium Voltage-Gated Channel Subfamily A Member 3 antibody
Anti-Hgk5 antibody
Anti-Hlk3 antibody
Anti-Hpcn3 antibody
Anti-Voltage-Gated K(+ Channel Hukiii antibody
Anti-Voltage-Gated Potassium Channel Subunit Kv1.3 antibody
Anti-KCNA3 antibody
Anti-HGK5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance