Apolipoprotein C2 from Human Plasma

Apolipoprotein C2 from Human Plasma
Catalog number: B2012178
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: 8.5 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Apo CII, ApoC2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Wang C, Yang Z, Xu E, Shen X, Wang X, Li Z, Yu H, Chen K, Hu Q, Xia X, Liu S, Guan W. Apolipoprotein C-II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway Clin Transl Med. 2021 Aug;11(8):e522.
2: Tcw J, Qian L, Pipalia NH, Chao MJ, Liang SA, Shi Y, Jain BR, Bertelsen SE, Kapoor M, Marcora E, Sikora E, Andrews EJ, Martini AC, Karch CM, Head E, Holtzman DM, Zhang B, Wang M, Maxfield FR, Poon WW, Goate AM. Cholesterol and matrisome pathways dysregulated in astrocytes and microglia Cell. 2022 Jun 23;185(13):2213-2233.e25.
3: Liu Y, Meng Y, Zhang T, Alachkar H. Deregulation of apolipoprotein C2 gene in cancer: A potential metabolic vulnerability Clin Transl Med. 2021 Jun;11(6):e406.
4: Zhang T, Yang J, Vaikari VP, Beckford JS, Wu S, Akhtari M, Alachkar H. Apolipoprotein C2 – CD36 Promotes Leukemia Growth and Presents a Targetable Axis in Acute Myeloid Leukemia Blood Cancer Discov. 2020 Sep;1(2):198-213.
5: Ma Q, Zhao Z, Sagare AP, Wu Y, Wang M, Owens NC, Verghese PB, Herz J, Holtzman DM, Zlokovic BV. Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism Mol Neurodegener. 2018 Oct 19;13(1):57.
6: Harney DJ, Hutchison AT, Hatchwell L, Humphrey SJ, James DE, Hocking S, Heilbronn LK, Larance M. Proteomic Analysis of Human Plasma during Intermittent Fasting J Proteome Res. 2019 May 3;18(5):2228-2240.
7: Johnson KE, Siewert KM, Klarin D, Damrauer SM; VA Million Veteran Program, Chang KM, Tsao PS, Assimes TL, Maxwell KN, Voight BF. The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study PLoS Med. 2020 Sep 11;17(9):e1003302.
8: Li Z, Du B, Li S, Lv X, Zhou S, Yu Y, Wang W, Zheng Z. Cloning and characterization of an apolipoprotein C2 promoter in the mouse central nervous system Neural Regen Res. 2013 Jan 15;8(2):156-61.
9: Selinger M, Věchtová P, Tykalová H, Ošlejšková P, Rumlová M, Štěrba J, Grubhoffer L. Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors Comput Struct Biotechnol J. 2022 May 30;20:2759-2777.
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